Desipramine Pretreatment Improves Sympathetic Remodeling and Ventricular Fibrillation Threshold after Myocardial Ischemia
Figure 4
GAP43 immunohistochemical staining of the infarct border zone (DAB color, ×200). (a) Sham-operated group. The distribution of GAP43-positive nerve fibers is orderly. (b) Control ischemic group. GAP43-positive nerve fibers in ventricular muscle increased significantly, it is also thickened and disordered. (c) Preischemic treatment group. (d) Delayed application group. The distribution of GAP43-positive nerve fibers after treatment with desipramine significantly improved.