Research Article

Urinary Neutrophil Gelatinase-Associated Lipocalin Is a Potential Biomarker for Renal Damage in Patients with Systemic Lupus Erythematosus

Table 2

24-hour urinary excretion of NGAL, IL-10, TGF-β1, and TNF-α in the study groups.a

SLE patientsControls
Active nephritisRenalNon-renalDCNC
Number243481412

NGAL (mg/day)50.41 (199.93)49.05 (114.45)21.78 (12.42)13.94 (12.53)7.65 (7.64)
IL-10 (ng/day)2.34 (16.81)3.45 (21.06)10.03 (18.27)13.12 (15.99)5.40 (24.09)
TGF-β1 (ng/day)41.54 (75.59)23.82 (69.08)16.17 (16.13)15.57 (14.94)7.83 (6.39)
TNF-α (ng/day)6.01 (15.23)5.85 (17.63)20.49 (24.26)26.68 (39.04)0 (13.65)

aData are shown as median (IQR).
NGAL: neutrophil gelatinase-associated lipocalin; IL-10: interleukin-10; TGF-β1: transforming growth factor-β1; TNF-α: tumor necrosis factor-α; SLE: systemic lupus erythematosus; DC: disease control; NC: normal control; IQR: interquartile range.