Inference of Tumor Phylogenies from Genomic Assays on Heterogeneous Samples

Figure 5

Inferred phylogenetic tree for the mixture components from the data of Navin et al. [14]. Nodes are labeled by component for the six inferred components C1–C6 and the normal component C0. Internal nodes are inferred ancestral states (Steiner nodes) and are each labeled by a unique identifier (8–12). Tree edges are labeled with the markers inferred to be amplified across each. Markers inferred to be lost along a given edge are shown in brackets and edges with no markers gained or lost are labeled “0.”