Development of ^𝟗𝟗𝐦𝐓𝐜-N4-NIM for Molecular Imaging of Tumor Hypoxia

Table 3

Radiation dose estimates for the reference adult for  ^99mTc-N4-NIM.

Target organ	rad/mCi	Human dose (mCi)	rad
Organs (5 rem annual/15 rem total)
Adrenals	6.56𝐸−03	20	0.131
Brain	5.03𝐸−04	20	0.010
Breasts	1.22𝐸−03	20	0.024
Gall bladder wall	4.28𝐸−03	20	0.086
Lli wall	1.53𝐸−03	20	0.031
Small int	2.97𝐸−03	20	0.059
Stomach	4.19𝐸−03	20	0.084
Uli wall	2.74𝐸−03	20	0.055
Heart wall	5.50𝐸−03	20	0.110
Kidneys	8.20𝐸−02	20	1.640
Liver	4.41𝐸−03	20	0.088
Lungs	5.05𝐸−03	20	0.101
Muscle	1.46𝐸−03	20	0.029
Pancreas	8.44𝐸−03	20	0.169
Bone surfaces	4.11𝐸−03	20	0.082
Skin	8.81𝐸−04	20	0.018
Testes	8.11𝐸−04	20	0.016
Thymus	1.69𝐸−03	20	0.034
Thyroid	9.93𝐸−04	20	0.020
Urine bladder wall	1.18𝐸−03	20	0.024
Uterus	1.65𝐸−03	20	0.033
Eff dose	3.41𝐸−03	20	0.068
Blood-forming organs (3 rem annual/5 rem total)
Ovaries	1.67𝐸−03	20	0.033
Red marrow	2.15𝐸−03	20	0.043
Spleen	3.27𝐸−02	20	0.654
Eff dose eq	9.73𝐸−03	20	0.195
Total body	2.26𝐸−03	20	0.045