Altered Polarization, Morphology, and Impaired Innate Immunity Germane to Resident Peritoneal Macrophages in Mice with Long-Term Type 2 Diabetes
Impaired chemotaxis and adhesion capacity of RPMs from 5-month db/db mice. FMLP induced migration of RPMs from normal mice (b) and db/db mice (d) was stained by Crystal Violet; while (a) and (c) were RPMs from normal and db/db mice, respectively, with no chemokine by crystal violet staining. The average CI (e) and AI (f) of RPMs of four independent experiments was quantified. Scale bars represent 50 μm. **P < 0.01 versus the control group.