BioMed Research International / 2012 / Article / Tab 1 / Research Article
Persistent Dystrophin Protein Restoration 90 Days after a Course of Intraperitoneally Administered Naked 2′OMePS AON and ZM2 NP-AON Complexes in mdx Mice Table 1 Injection schedule.
Group (
n
∘
of mice) Formulations
N
∘
of I.P. injections (1/week)Sacrifice Naked AON (
𝑛
=
4
) M23D-AON
𝜇
g/injection (7.5 mg/Kg/week) 7 12 weeks after last injection ZM2-AON (
𝑛
=
4
) ZM2 2.5 mg
𝜇
g/injection (7.5 mg/Kg/week) 7 12 weeks after last injection ZM2 (
𝑛
=
4
) ZM2 2.5 mg/injection 7 12 weeks after last injection Not Treated (
𝑛
=
4
) Not Treated Not Treated 12 weeks after last injection
