Curcumin Attenuates Gastric Cancer Induced by N-Methyl-N-Nitrosourea and Saturated Sodium Chloride in Rats
Figure 1
Macroscopic (a) and microscopic (b–d, H&E staining, 40x) appearance of squamous cell carcinoma (SCC) in the forestomachs. The multiple polypoid tumors developed in the stomach after MNU and saturated NaCl administration (a). SCCs in the gastric epithelium show the invasion of cancerous tissue with dyskeratosis through submucosal layer (b), muscle layer (c), or serosa (d). Note: the arrows indicate SCC with submucosal invasion (b), muscle-layer invasion (c), and stomach perforation (d). MM: muscularis mucosae, SM: submucosa, and M: muscle layer.
