Research Article

An In Vivo Rabbit Model for the Evaluation of Antimicrobial Peripherally Inserted Central Catheter to Reduce Microbial Migration and Colonization as Compared to an Uncoated PICC

Table 6

Infection prevention in the tissue samples: the total number of samples where significant (≥3.0 Log) bacterial load was recovered (from sample locations 4, 6, 8, and 10) is divided by the total number of catheters/tracts in each group. This is separated by sample type (tissue and catheter).

Sample dayTest catheter
tunnel
Control catheter tunnel 𝑃

2140% (6 of 15 tracts)80% (12 of 15 tracts)0.030216 (S)
306% (1 of 15 tracts)76% (10 of 13 tracts)0.000203 (S)

*Fisher exact test for statistical significance (for statistical significance (S), 𝑃 0 . 0 5 ).