Increased Expression of microRNA-17 Predicts Poor Prognosis in Human Glioma
Figure 1
microRNA-17 (miR-17) expression in 108 glioma and 20 normal brain tissues detected by quantitative real-time polymerase chain reaction (qRT-PCR) analysis. Compared with normal brain tissues, miR-17 expression was significantly higher in glioma tissues (: versus , , Figure 1), corresponding to the glioma WHO grades. The statistic results showed that its expression in high-grade (III-IV; : ) and low-grade (I-II; : ) gliomas were both significantly higher than that in normal brains tissues (both ). Moreover, there was also a significant difference in miR-17 expression between high-grade (III-IV) and low-grade (I-II) glioma tissue specimens ().
