Table of Contents Author Guidelines Submit a Manuscript
Table of Contents Alerts

To receive news and publication updates for BioMed Research International, enter your email address in the box below.

Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 985020, 8 pages
http://dx.doi.org/10.1155/2012/985020
Research Article

Serum Peptidome Patterns of Colorectal Cancer Based on Magnetic Bead Separation and MALDI-TOF Mass Spectrometry Analysis

Nai-Jun Fan,1 Chun-Fang Gao,1 Xiu-Li Wang,1 Guang Zhao,1 Qing-Yin Liu,2 Yuan-Yao Zhang,1 and Bao-Guo Cheng3

1Institute of Anal-Colorectal Surgery, No. 150 Hospital of PLA, LuoYang 471000, China
2The Clinical Laboratory, No. 150 Hospital of PLA, LuoYang 471000, China
3Department of Radiology, The First Affiliated Hospital of Henan Science and Technology University, LuoYang, China

Received 2 February 2012; Accepted 14 June 2012

Academic Editor: Saulius Butenas

Copyright © 2012 Nai-Jun Fan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward, and D. Forman, “Global cancer statistics,” CA Cancer Journal for Clinicians, vol. 61, no. 2, pp. 69–90, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Jemal, R. Siegel, J. Xu, and E. Ward, “Cancer statistics, 2010,” CA Cancer Journal for Clinicians, vol. 60, no. 5, pp. 277–300, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. L. Ciccolallo, R. Capocaccia, M. P. Coleman et al., “Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis and surgery,” Gut, vol. 54, no. 2, pp. 268–273, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. B. K. Edwards, E. Ward, B. A. Kohler et al., “Annual report to the nation on the status of cancer, 1975–2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates,” Cancer, vol. 116, no. 3, pp. 544–573, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. R. A. Smith, V. Cokkinides, D. Brooks, D. Saslow, M. Shah, and O. W. Brawley, “Cancer screening in the United States, 2011: a review of current American Cancer Society guidelines and issues in cancer screening,” CA Cancer Journal for Clinicians, vol. 61, no. 1, pp. 8–30, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. E. Phizicky, P. I. H. Bastiaens, H. Zhu, M. Snyder, and S. Fields, “Protein analysis on a proteomic scale,” Nature, vol. 422, no. 6928, pp. 208–215, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. H. J. Issaq, Z. Xiao, and T. D. Veenstra, “Serum and plasma proteomics,” Chemical Reviews, vol. 107, no. 8, pp. 3601–3620, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. Y. Dai, C. Hu, L. Wang et al., “Serum peptidome patterns of human systemic lupus erythematosus based on magnetic bead separation and MALDI-TOF mass spectrometry analysis,” Scandinavian Journal of Rheumatology, vol. 39, no. 3, pp. 240–246, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. E. F. Petricoin, C. Belluco, R. P. Araujo, and L. A. Liotta, “The blood peptidome: a higher dimension of information content for cancer biomarker discovery,” Nature Reviews Cancer, vol. 6, no. 12, pp. 961–967, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. L. H. Liu, B. E. Shan, Z. Q. Tian et al., “Potential biomarkers for esophageal carcinoma detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry,” Clinical Chemistry and Laboratory Medicine, vol. 48, no. 6, pp. 855–861, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. W. Sui, L. Huang, Y. Dai, J. Chen, Q. Yan, and H. Huang, “Proteomic profiling of renal allograft rejection in serum using magnetic bead-based sample fractionation and MALDI-TOF MS,” Clinical and Experimental Medicine, vol. 10, no. 4, pp. 259–268, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J. M. Koomen, D. Li, L. C. Xiao et al., “Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discovery,” Journal of Proteome Research, vol. 4, no. 3, pp. 972–981, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. J. Villanueva, J. Philip, D. Entenberg et al., “Serum peptide profiling by magnetic particle-assisted, automated sample processing and MALDI-TOF mass spectrometry,” Analytical Chemistry, vol. 76, no. 6, pp. 1560–1570, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. G. S. Omenn, “The Human Proteome Organization Plasma Proteome Project pilot phase: reference specimens, technology platform comparisons, and standardized data submissions and analyses,” Proteomics, vol. 4, no. 5, pp. 1235–1240, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Yao, H. Chen, H. Lin, C. Deng, and X. Zhang, “Enrichment of peptides in serum by C8-functionalized magnetic nanoparticles for direct matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis,” Journal of Chromatography A, vol. 1185, no. 1, pp. 93–101, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. J. R. Whiteaker, L. Zhao, H. Y. Zhang et al., “Antibody-based enrichment of peptides on magnetic beads for mass-spectrometry-based quantification of serum biomarkers,” Analytical Biochemistry, vol. 362, no. 1, pp. 44–54, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. M. West-Nørager, C. D. Kelstrup, C. Schou, E. V. Høgdall, C. K. Høgdall, and N. H. H. Heegaard, “Unravelling in vitro variables of major importance for the outcome of mass spectrometry-based serum proteomics,” Journal of Chromatography B, vol. 847, no. 1, pp. 30–37, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Shin, L. Cazares, H. Schneider et al., “Serum biomarkers to differentiate benign and malignant mammographic lesions,” Journal of the American College of Surgeons, vol. 204, no. 5, pp. 1065–1071, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Baumann, U. Ceglarek, G. M. Fiedler, J. Lembcke, A. Leichtle, and J. Thiery, “Standardized approach to proteome profiling of human serum based on magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry,” Clinical Chemistry, vol. 51, no. 6, pp. 973–980, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. C. C. Compton and F. L. Greene, “The staging of colorectal cancer: 2004 and beyond,” Ca-A Cancer Journal for Clinicians, vol. 54, no. 6, pp. 295–308, 2004. View at Google Scholar · View at Scopus
  21. R. Ketterlinus, S. Y. Hsieh, S. H. Teng, H. Lee, and W. Pusch, “Fishing for biomarkers: analyzing mass spectrometry data with the new ClinProTools software,” BioTechniques, supplement, pp. 37–40, 2005. View at Google Scholar · View at Scopus
  22. J. A. Swets, “Measuring the accuracy of diagnostic systems,” Science, vol. 240, no. 4857, pp. 1285–1293, 1988. View at Google Scholar · View at Scopus
  23. B. Zethelius, L. Berglund, J. Sundström et al., “Use of multiple biomarkers to improve the prediction of death from cardiovascular causes,” The New England Journal of Medicine, vol. 358, no. 20, pp. 2107–2116, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. J. P. Tolson, T. Flad, V. Gnau et al., “Differential detection of S100A8 in transitional cell carcinoma of the bladder by pair wise tissue proteomic and immunohistochemical analysis,” Proteomics, vol. 6, no. 2, pp. 697–708, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. A. J. Cheng, L. C. Chen, K. Y. Chien et al., “Oral cancer plasma tumor marker identified with bead-based affinity-fractionated proteomic technology,” Clinical Chemistry, vol. 51, no. 12, pp. 2236–2244, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Alagaratnam, B. J. A. Mertens, J. C. Dalebout et al., “Serum protein profiling in mice: identification of Factor XIIIa as a potential biomarker for muscular dystrophy,” Proteomics, vol. 8, no. 8, pp. 1552–1563, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. C. Chinello, E. Gianazza, I. Zoppis et al., “Serum biomarkers of renal cell carcinoma assessed using a protein profiling approach based on ClinProt technique,” Urology, vol. 75, no. 4, pp. 842–847, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Du, S. Yang, X. Lin et al., “Use of anchorchip-time-of-flight spectrometry technology to screen tumor biomarker proteins in serum for small cell lung cancer,” Diagnostic Pathology, vol. 5, article 60, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. G. Ikonomou, M. Samiotaki, and G. Panayotou, “Proteomic methodologies and their application in colorectal cancer research,” Critical Reviews in Clinical Laboratory Sciences, vol. 46, no. 5-6, pp. 319–342, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. E. F. Petricoin, A. M. Ardekani, B. A. Hitt et al., “Use of proteomic patterns in serum to identify ovarian cancer,” The Lancet, vol. 359, no. 9306, pp. 572–577, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. Y. D. Chen, S. Zheng, J. K. Yu, and X. Hu, “Artificial neural networks analysis of surface-enhanced laser desorption/ionization mass spectra of serum protein pattern distinguishes colorectal cancer from healthy population,” Clinical Cancer Research, vol. 10, no. 24, pp. 8380–8385, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. X. P. Liu, J. Shen, Z. F. Li, L. Yan, and J. Gu, “A serum proteomic pattern for the detection of colorectal adenocarcinoma using surface enhanced laser desorption and ionization mass spectrometry,” Cancer Investigation, vol. 24, no. 8, pp. 747–753, 2006. View at Publisher · View at Google Scholar · View at Scopus
  33. N.-J. Fan, C.-F. Gao, and X.-L. Wang, “Identification of regional lymph node involvement of colorectal cancer by serum SELDI proteomic patterns,” Gastroenterology Research and Practice, vol. 2011, Article ID 784967, 6 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. G. L. Hortin, “The MALDI-TOF mass spectrometric view of the plasma proteome and peptidome,” Clinical Chemistry, vol. 52, no. 7, pp. 1223–1237, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. A. Navare, M. Zhou, J. McDonald, F. G. Noriega, M. C. Sullards, and F. M. Fernandez, “Serum biomarker profiling by solid-phase extraction with particle-embedded micro tips and matrix-assisted laser desorption/ionization mass spectrometry,” Rapid Communications in Mass Spectrometry, vol. 22, no. 7, pp. 997–1008, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. W. C. S. Cho, “Contribution of oncoproteomics to cancer biomarker discovery,” Molecular Cancer, vol. 6, article 25, 2007. View at Publisher · View at Google Scholar · View at Scopus