Leflunomide as a Corticosteroid-Sparing Agent in Giant Cell Arteritis and Polymyalgia Rheumatica: A Case Series

Table 1

Baseline characteristics of the enrolled patients.

	PMR (#12)	GCA (#11)	𝑃 values
Mean age in years (SD)	67.4 (7.5)	71.1 (6.0)	0.21
Median disease duration in months (range)	14 (4–78)	20 (4–120)	0.50
Number of patients used methotrexate before (%)	3 (25.0)	7 (63.6)	0.06
Median prednisolone dose in mg (range)	10.5 (5–17)	10.4 (7–20)	0.95
Median CRP in mg/L (interquartile range)	9.5 (26.2)	12.0 (24)	0.70
Mean leflunomide dose in mg (CI 95%)	14 (10.8–17.4)	12.7 (9.5–15.8)	0.49

PMR: polymyalgia rheumatica, GCA: giant cell arteritis, SD: standard deviation, CRP: C-reactive protein, CI: confidence interval, #: number of patients enrolled.