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BioMed Research International
Volume 2013, Article ID 128594, 8 pages
http://dx.doi.org/10.1155/2013/128594
Research Article

Assessment of Cytotoxicity, Fetotoxicity, and Teratogenicity of Plathymenia reticulata Benth Barks Aqueous Extract

1Post-Graduate Program in Pharmaceutical Sciences, University of Sorocaba, UNISO, Rodovia Raposo Tavares, km 92.5, 18023-000 Sorocaba, SP, Brazil
2Federal University of Pampa, CIPBiotec, UNIPAMPA, Avenida Antonio Trilha 1847, 97300-000 São Gabriel, RS, Brazil
3Post-Graduate Course in Environmental Sciences, PGCiamb, Federal University of Tocantins, UFT, Avenida NS 15 ALC NO 14, 109 Norte, 77001-090 Tocantins, Brazil
4Federal University of São Paulo, UNIFESP, R. Prof. Artur Riedel 275, 09972-270 Diadema, SP, Brazil

Received 29 August 2013; Revised 12 November 2013; Accepted 13 November 2013

Academic Editor: Marina Soković

Copyright © 2013 Lia de Barros Leite Albuquerque et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. J. King and S. Rodrigo, “Plathyterpol, a diterpene from Plathymenia reticulata,” Chemical Communications, no. 12, article 575, 1967. View at Publisher · View at Google Scholar · View at Scopus
  2. F. J. A. Matos, A. A. Craveiro, and M. A. M. A. De Maurera, “Furan diterpenes of the Plathymenia genus,” Journal of Natural Products, vol. 47, no. 4, pp. 581–584, 1984. View at Google Scholar · View at Scopus
  3. R. D. S. Leal, M. A. S. Lima, and E. R. Silveira, “Cassane diterpenes from Plathymenia reticulata,” Journal of the Brazilian Chemical Society, vol. 14, no. 1, pp. 120–125, 2003. View at Google Scholar · View at Scopus
  4. A. Pott, V. J. Pott, and A. A. Bueno Sobrinho, “Plantas úteis à sobrevivência no Pantanal,” Proceedings of the Simpósio sobre Recursos Naturais e Sócio-econômicos do Pantanal, Corumbá, Brazil, 2004.
  5. T. T. Fernandes, A. T. Santos, and F. C. Pimenta, “Atividade antimicrobiana das plantas Plathymenia reticulata, Hymenaea courbaril e Guazuma ulmifolia,” Revista de Patologia Tropical, vol. 34, pp. 113–122, 2005. View at Google Scholar
  6. C. E. M. De Toledo, E. A. Britta, L. F. Ceole et al., “Antimicrobial and cytotoxic activities of medicinal plants of the Brazilian cerrado, using Brazilian cachaa as extractor liquid,” Journal of Ethnopharmacology, vol. 133, no. 2, pp. 420–425, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. M. G. Santos, S. F. Lolis, and C. A. Dal Belo, “Levantamentos Etnobotânicos realizados em duas comunidades de remanescentes de negros da região do Jalapão, Estado do Tocantins,” in Sociabilidade Negras. Comunidades Remanescentes, Escravidão e Cultura, A. L. Pires, S. Cardoso, and R. Oliveira, Eds., pp. 29–49, Daliana, Belo Horizonte, Brazil, 2006. View at Google Scholar
  8. S. Norton, “Toxic effects of plants,” in Casarett and Doull’s Toxicology: the basic Science of poisons, pp. 965–976, McGraw-Hill, New York, NY, USA, 2001. View at Google Scholar
  9. R. F. Melo, N. M. Farrapo, D. S. Rocha Jr. et al., “Antiophidian mechanisms of medicinal plants,” in Flavonoids: Biosynthesis, Biological Effects and Dietary Sources, R. B. Keller, Ed., pp. 249–262, Nova Science Publishers, New York, NY, USA, 2009. View at Google Scholar
  10. N. M. Farrapo, G. A. A. Silva, K. N. Costa et al., “Inhibition of Bothrops jararacussu venom activities by Plathymenia reticulata Benth extracts,” Journal of Venom Research, vol. 2, pp. 52–58, 2011. View at Google Scholar
  11. A. Della Torre, L. B. L. Albuquerque, N. M. Farrapo et al., “Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata benth,” Journal of Venomous Animals and Toxins Including Tropical Diseases, vol. 17, no. 2, pp. 190–198, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. A. R. Carvalho, T. J. Lacerda, F. E. Oliveira, and S. E. Santos, “Extratos de plantas medicinais como estratégia para o controle de doenças fúngicas do inhame (Dioscorea sp.) no nordeste,” in II Simpósio Nacional sobre as Culturas do Inhame e do Taro—Empresa Estadual de Pesquisa Agropecuária da Paraíba, EMEPA, João Pessoa, Brazil, 2002. View at Google Scholar
  13. J. M. Rogers and R. J. Kavlock, “Developmental toxicology,” in Casarett and Doull’s Toxicology: the basic Science of poisons, pp. 351–386, McGraw-Hill, New York, NY, USA, 2001. View at Google Scholar
  14. OECD, “Phototox Version 2. 0,” in Chemical Testing—Guidelines, section 4: software, Organisation for Economic Co-operation and Development, Paris, France, 2010, http://www.oecd.org/document/62/0,3343,en_2649_34377_44706494_1_1_1_1,00.html.
  15. L. A. D. Francia-Farje, D. S. Silva, G. T. Volpato et al., “Sibutramine effects on the reproductive performance of pregnant overweight and non-overweight rats,” Journal of Toxicology and Environmental Health A, vol. 73, no. 13-14, pp. 985–990, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. ICCVAM, “Peer review panel report: the use of in vitro basal cytotoxicity test methods for estimating starting doses for acute oral systemic toxicity testing,” NIH publication no. 07-4519, Research Triangle Park, National Toxicology Program, 2006, http://iccvam.niehs.nih.gov/docs/acutetox_docs/ATpanelrpt06/ATpanelrpt.pdf#search=peer%20review%20panel%20report:%20the%20use%20or%20in%20vitro%20vasal%20cytotoxicity.
  17. N. M. Esteves-Pedro, A. C. D. Rodas, C. A. Dal Belo, Y. Oshima-Franco, M. G. Dos Santos, and P. S. Lopes, “Implementation of the three Rs in the human hazard assessment of Brazilian medicinal plants: an evaluation of the cytotoxic and genotoxic potentials of Dipteryx alata vogel,” ATLA Alternatives to Laboratory Animals, vol. 39, no. 2, pp. 189–196, 2011. View at Google Scholar · View at Scopus
  18. M. Gerenutti, F. S. Del Fiol, and F. C. Groppo, “Reproductive performance of pregnant rats and embryotoxic effects of ciprofloxacin,” Pharmazie, vol. 61, no. 1, pp. 79–80, 2006. View at Google Scholar · View at Scopus
  19. M. Gerenutti, A. F. Rollo Oliveira Prestes, M. Glauzer Silva et al., “The effect of Cecropia glazioui Snethlage on the physical and neurobehavioral development of rats,” Pharmazie, vol. 63, no. 5, pp. 398–404, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. N. M. Esteves-Pedro, T. Borim, V. S. Nazato et al., “In vitro and in vivo safety evaluation of Dipteryx alata Vogel extract,” BMC Complementary and Alternative Medicine, vol. 12, article 9, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. U.S. EPA, “Guidelines for the Health Assessment of Suspected Developmental Toxicants,” Federal Register 51 FR 34040, 1986, Proposed Amendments Federal Register 54 FR 9386, 1989. View at Google Scholar
  22. P. Randazzo-Moura, M. G. Silva, Y. Oshima-Franco, F. C. Groppo, and M. Gerenutti, “The effect of aqueous extract of Cecropia glazioui Snethlage (Embauba) in the rat fetal development,” Chinese Medicine, vol. 2, pp. 115–119, 2011. View at Google Scholar
  23. D. C. Damasceno and W. G. Kempinas, Anomalias Congênitas—Estudos Experimentais, Coopmed, Belo Horizonte, Brazil, 2008.
  24. K. A. Keller, “Developmental and reproductive toxicology,” in Toxicology Testing Handbook: Principles, Applications and Data Interpretation, D. Jacobson-Kram and K. A. Keller, Eds., pp. 195–252, Marcel Dekker, New York, NY, USA, 2006. View at Google Scholar
  25. A. M. McNamara, P. D. Magidson, C. Linster, D. A. Wilson, and T. A. Cleland, “Distinct neural mechanisms mediate olfactory memory formation at different timescales,” Learning and Memory, vol. 15, no. 3, pp. 117–125, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. G. P. Daston, “Relationships between maternal and developmental toxicity,” in Developmental Toxicology, C. A. Kimmel and J. Buelke-Sam, Eds., pp. 189–212, Raven Press, New York, NY, USA, 1994. View at Google Scholar
  27. N. Chernoff, J. M. Rogers, A. J. Alles et al., “Cell cycle alterations and cell death in cyclophosphamide teratogenesis,” Teratogenesis Carcinogenesis and Mutagenesis, vol. 9, no. 4, pp. 199–209, 1989. View at Google Scholar · View at Scopus
  28. J. R. Galler and G. Zartarian, “Reproductive performance in rats with different histories of malnutrition,” British Journal of Nutrition, vol. 45, no. 2, pp. 251–255, 1981. View at Google Scholar · View at Scopus
  29. S. C. Langley and A. A. Jackson, “Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets,” Clinical Science, vol. 86, no. 2, pp. 217–222, 1994. View at Google Scholar · View at Scopus
  30. C. D. Robert, N. Li, R. Caicedo et al., “Metabolic effects of different protein intakes after short term undernutrition in artificially reared infant rats,” Early Human Development, vol. 85, no. 1, pp. 41–49, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Torchinsky, L. Lishanski, O. Wolstein et al., “NF-κB DNA-binding activity in embryos responding to a teratogen,cyclophosphamide,” BMC Developmental Biology, vol. 2, article 1, pp. 1–11, 2002. View at Publisher · View at Google Scholar · View at Scopus
  32. U. S. U.S. EPA, “Guidelines for the Health Assessment of Suspected Developmental Toxicants,” Federal Register 51 FR 34040, 1986, proposed amendments Federal Register 54 FR 9386, 1989. View at Google Scholar