Human Mesenchymal Stem Cells Provide Protection against Radiation-Induced Liver Injury by Antioxidative Process, Vasculature Protection, Hepatocyte Differentiation, and Trophic Effects

Table 3

Frequency of human cells in livers of irradiated (TBI) NOD/SCID mice after hMSC infusion. The frequency of hMSCs engrafted in liver was quantified using a PCR detection of the human β-globin gene in mouse liver from 3 to 60 days after TBI. The hMSC engraftment rate was significantly increased at 30 days in the liver following TBI, when compared to the 15th day. All values are expressed as the mean and the standard error of the mean (SEM), 𝑛=10.

Days after TBI	3	7	15	30	60
% human cells (mean, 𝑛=10)	0.07%	0.09%	0.11%	3.08%	2.52%
SEM	0.01	0.04	0.12	1.12	0.91