Glutamine and Alanyl-Glutamine Increase RhoA Expression and Reduce Clostridium difficile Toxin-A-Induced Intestinal Epithelial Cell Damage

Figure 5

Effect of TcdA of Clostridium difficile and alanyl-glutamine on TUNEL cells/mm² percent. The IEC-6 cells were treated for 24 h medium alone (control), TcdA (10 ng/mL), TcdA + Ala-Gln (treated with TcdA 10 ng/mL and Ala-Gln 10 mM), and Ala-Gln 10 mM. ^∗𝑃<0.05 compared to control. ^#𝑃<0.05 compared to TcdA 100 ng/mL.