Research Article

In Silico Prediction and In Vitro Characterization of Multifunctional Human RNase3

Table 2

Secondary structures of correspondent HBRs in hRNaseA members.

HBR1HBR2HBR3PDB number

hRNase1LoopLoopβ-strand2K11
hRNase2LoopLoopβ-strand2C01
hRNase3LoopLoopβ-strand2KB5
hRNase4Loopβ-strandβ-strand1RNF
hRNase5LoopLoopβ-strand1H53
hRNase6LoopLoopβ-strand2HKY*
hRNase7LoopLoopβ-strand2HKY
hRNase8LoopLoopβ-strand2HKY*

The structures of hRNase1, 2, 3, 4, 5, and 7 are collected from protein data bank (PDB), and those of RNase6, 8 were simulated by database (PS)2—Protein Structure Prediction Server (http://ps2.life.nctu.edu.tw/). *Denotes simulated structures using hRNase7 as template.