BioMed Research International / 2013 / Article / Tab 3

Clinical Study

Primary Immunodeficiency Diseases at Reference and High-Specialty Hospitals in the State of Guanajuato, Mexico

Table 3

Clinical data on etiological agents of infectious diseases in the studied group of patients.

No.GenderDiagnosisInfectious diseases
(number of episodes)
Etiologic agentsComorbidity

1FemaleCombined immunodeficiencyPneumonia (3), urinary tract infection (1)Burkholderia cepacia, E. Coli 
Candida albicans.
2FemaleCVIDPneumonia (4)Nonisolated pathogensDown syndrome, Hypothyroidism
3MaleSelective IgA deficiencyRecurrent URTI Nonisolated pathogensNone
4FemaleAtaxia-telangiectasiaTonsillitis (3), gastronitestinal infection (1)S. pyogenes None
5MaleCVIDPneumonia (3), sinusitis (4)S. pneumonia None
6MaleSelective IgA deficiencyRecurrent URTINonisolated pathogensFood allergy
7MaleTHIRecurrent URTINonisolated pathogensNone
8MaleIsolated IgG subclass deficiencyPneumonia (1), otitis media (5), sinusitis (1).
Gastrointestinal infection (2)
S. pneumoniae Hypertrophic cardiomyopathy
9MaleIsolated IgG subclass deficiencyOtitis media (1), Sinusitis (3)Nonisolated pathogensNone
10MaleX-linked agammaglobulinemiaPneumonia (5), sinusitis (3), otitis (5).
Meningitis, recurrent URTI
S. epidermidis,  
S. pneumoniae
11MaleX-linked agammaglobulinemiaPneumonia (3), sinusitis (2)Klebsiella pneumoniae,
Candida sp.,
S. pneumoniae
Rheumatoid arthritis
12MaleX-linked agammaglobulinemiaPneumonia (2), sinusitis (3), pyoderma gangrenosumPseudomonas spAllergic rhinitis
13Female CVIDPneumonia (8), sinusitis (2)Nonisolated pathogensNone
14FemaleCVIDGastrointestinal infection (4), pneumonia (3)Giardia lamblia Autoimmune thyroiditis, Hypothyroidism
15FemaleCVIDGastro intestinal infection (5), pneumonia (2), intestinal tuberculosisMycobacterium tuberculosis Arthritis
16MaleCVIDPneumonia (7)Nonisolated pathogensAllergic rhinitis
17FemaleCVIDPneumonia (2), sinusitis (2)Not available dataNone
18FemaleTHIRecurrent URTINonisolated pathogensDown syndrome, IAC
19MaleChronic granulomatous diseasePneumonia (10), skin abscesses, lung abscessSerratia marcescens,
S. aureus.,
Stenotrophomonas maltophilia, E. Coli
20MaleChronic mucocutaneous candidiasisPersistent thrush, onychomycosis, recurrent URTI
skin abscesses, varicella
Candida sp., Klebsiella pneumoniae,
Herpes zoster
21FemaleHereditary angioedemaURTI (2/year)Nonisolated pathogensNone
22MaleHyper-IgE syndromeSkin abscesses, pneumonia (1), recurrent URTI
otitis (9)
S. aureus Cow’s milk allergy, GERD
23FemaleChronic mucocutaneous candidiasisPersistent thrush, onychomycosis, pneumonia (11)Candida sp.Hypothyroidism, cow’s milk allergy, GERD
24MaleCyclic neutropeniaPeriodontitis, recurrent URTI, pneumonia (3).
Otitis (3), Sinusitis (1), gastrointestinal infection (2)
Nonisolated pathogensNone
25MaleChromosome 22q11.2 deletion Pneumonia (4)S. pneumonia Cardiopathy, Pulmonary hypertension
26FemaleCVIDPneumonia (4), UTI (2)Moraxella catarrhalis, S. viridans Allergic rhinitis

CVID: common variable immunodeficiency disorders; GERD: gastroesophageal reflux disease; IAC: interauricular communication; THI: transient hypogammaglobulinemia of infancy; URTI: upper respiratory tract infections; UTI: urinary tract infection.

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