The Pyridoxal 5′-Phosphate (PLP)-Dependent Enzyme Serine Palmitoyltransferase (SPT): Effects of the Small Subunits and Insights from Bacterial Mimics of Human hLCB2a HSAN1 Mutations
Figure 6
Structural models of HSAN1 mutant mimic Sp SPT V246M mutation using the Sp SPT-L-serine external aldimine structure (PDB:2W8J). (a) Wild-type V246. (b) Mutation of residue 246 to a methionine. Residue 246 is shown in yellow. The models and figures were generated using PyMol software.
