Research Article
Design Expert Supported Mathematical Optimization and Predictability Study of Buccoadhesive Pharmaceutical Wafers of Loratadine
Table 5
Results of analysis of variance (ANOVA) for measured responses.
| | Parameter | SS | df | MS | | Significance |
| | Bioadhesion () |
| | Model | 2718.21 | 5 | 543.64 | 11.26 | 0.0369 | | Residual | 144.80 | 3 | 48.27 | — | — | | Cor total | 2863.01 | 8 | — | — | — |
| | Disintegration time () |
| | Model | 2.77 | 5 | 0.55 | 58.82 | 0.0034 | | Residual | 0.028 | 3 | | — | — | | Cor total | 2.80 | 8 | — | — | — |
| | % Swelling index () |
| | Model | 1799.79 | 5 | 359.96 | 58626.95 | <0.0001 | | Residual | 0.018 | 3 | | — | — | | Cor total | 1799.81 | 8 | — | — | — |
| | () |
| | Model | 36025.00 | 5 | 7205.00 | 15.72 | 0.0231 | | Residual | 1375 | 3 | 458.33 | | | | Cor total | 37400 | 8 | — | — | — |
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df: degree of freedom; SS: sum of square; MS: mean square; : Fischer’s ratio.
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