Table 2
Identified DNA variants and the Hardy-Weinberg equilibrium of 10 SNPs in the TNNT2 gene in the DCM patients and control subjects.
| Markers | Location of nucleotide change | Amino acid change | Note | Obs HET | Expt HET | HWE (P) | MAF |
| rs7521796 | Intron 201330019 A>G | Noncoding | Novel noncoding SNP | 0.115 | 0.115 | 1 | 0.061 | rs2275862 | Intron 201330366 C>G | Non-coding | Novel non-coding SNP | 0.329 | 0.319 | 0.7683 | 0.199 | rs3729547 | 201334382 T>C | Synonymous Ile [I] | Reported synonymous | 0.504 | 0.484 | 1 | 0.41 | rs10800775 | Intron 201336386 C>T | Non-coding | Novel non-coding SNP | 0.474 | 0.448 | 0.771 | 0.339 | rs1892028 | Intron 201336641 A>G | Non-coding | Novel non-coding SNP | 0.489 | 0.498 | 0.7396 | 0.47 | rs3729843 | Intron 201336984 G>A | Non-coding | Reported non-coding SNP | 0.285 | 0.331 | 0.5949 | 0.21 | rs3729842 | Intron 201337170 C>T | Non-coding | Reported non-coding SNP | 0.225 | 0.241 | 0.3594 | 0.14 | rs12563114 | Intron 201344908 C>T | Non-coding | Novel non-coding SNP | 0.081 | 0.084 | 0.5638 | 0.044 | rs12564445 | Intron 201345487 G>A | Non-coding | Novel non-coding SNP | 0.435 | 0.427 | 0.7891 | 0.309 | rs4915232 | 5′ near gene 201347946 A>G | Non-coding | Novel non-coding SNP | 0.535 | 0.499 | 0.7407 | 0.482 |
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Note: Obs HET: observed heterozygosity, Expt HET: expected heterozygosity, HWE (P): P value from the Hardy-Weinberg equilibrium test, and MAF: minor allele frequency.
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