Research Article
TNNT2 Gene Polymorphisms Are Associated with Susceptibility to Idiopathic Dilated Cardiomyopathy in the Han Chinese Population
Table 3
Genotype and allele frequencies of the SNPs from the TNNT2 gene in the DCM patients and control subjects.
| | Marker | Genotype | , P value | Allele | , P value | OR (95% CI) |
| | rs7521796 | A/A | A/G | G/G | | A | G | | 1.303 (0.613–2.772) | | Patients | 87 (0.897) | 10 (0.103) | 0 (0) | | 184 (0.948) | 10 (0.052) | | | | Controls | 165 (0.873) | 23 (0.122) | 1 (0.005) | | 353 (0.934) | 25 (0.066) | | | | rs2275862 | C/C | C/G | G/G | | C | G | | 1.562 (0.987–2.471) | | Patients | 69 (0.711) | 26 (0.268) | 2 (0.021) | | 164 (0.845) | 30 (0.155) | | | | Controls | 113 (0.598) | 68 (0.360) | 8 (0.042) | | 294 (0.778) | 84 (0.222) | | | | rs3729547 | C/C | T/C | T/T | | C | T | | 0.650 (0.453–0.934) | | Patients | 8 (0.084) | 49 (0.516) | 38 (0.4) | | 65 (0.342) | 125 (0.658) | | | | Controls | 37 (0.196) | 94 (0.497) | 58 (0.307) | | 168 (0.444) | 210 (0.556) | | | | rs10800775 | C/C | C/T | T/T | | C | T | | 1.486 (1.019–2.169) | | Patients | 47 (0.49) | 44 (0.458) | 5 (0.052) | | 138 (0.719) | 54 (0.281) | | | | Controls | 74 (0.392) | 91 (0.481) | 24 (0.127) | | 239 (0.632) | 139 (0.368) | | | | rs1892028 | A/A | A/G | G/G | | A | G | | 1.578 (1.090–2.291) | | Patients | 30 (0.357) | 42 (0.5) | 12 (0.143) | | 102 (0.607) | 66 (0.393) | | | | Controls | 46 (0.253) | 88 (0.484) | 48 (0.264) | | 180 (0.495) | 184 (0.505) | | | | rs3729843 | A/A | A/G | G/G | | A | G | | 1.912 (1.265–2.890) | | Patients | 12 (0.126) | 30 (0.316) | 53 (0.558) | | 54 (0.284) | 136 (0.716) | | | | Controls | 7 (0.037) | 51 (0.270) | 131 (0.693) | | 65 (0.172) | 313 (0.828) | | | | rs3729842 | C/C | C/T | T/T | | C | T | | 1.158 (0.697–1.925) | | Patients | 74 (0.763) | 21 (0.216) | 2 (0.021) | | 169 (0.871) | 25 (0.129) | | | | Controls | 139 (0.739) | 43 (0.229) | 6 (0.032) | | 321 (0.854) | 55 (0.146) | | | | rs12563114 | C/C | C/T | T/T | | C | T | | 0.899 (0.390–2.07) | | Patients | 87 (0.906) | 9 (0.094) | 0 (0) | | 183 (0.953) | 9 (0.047) | | | | Controls | 174 (0.921) | 14 (0.074) | 1 (0.005) | | 362 (0.958) | 16 (0.042) | | | | rs12564445 | A/A | A/G | G/G | | A | G | | 0.663 (0.450–0.977) | | Patients | 6 (0.062) | 37 (0.381) | 54 (0.557) | | 49 (0.253) | 145 (0.747) | | | | Controls | 20 (0.106) | 87 (0.463) | 81 (0.431) | | 127 (0.338) | 249 (0.662) | | | | rs4915232 | A/A | A/G | G/G | | A | G | | 1.155 (0.816–1.635) | | Patients | 25 (0.258) | 55 (0.567) | 17 (0.175) | | 105 (0.541) | 89 (0.459) | | | | Controls | 46 (0.246) | 97 (0.519) | 44 (0.235) | | 189 (0.505) | 185 (0.495) | | |
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