Time Series Expression Analyses Using RNA-seq: A Statistical Approach

Table 2

Statistical evolutionary trajectory index (SETI) of the top candidate genes where FDR is controlled at less than 0.05 in a sheep model data. The gene expression level is fitted on smooth spline function, autocorrelation of residuals is measured, and corresponding statistical significance is tested. In addition, trimmed mean of bootstrap and 95 percent of confidence interval are also provided in the table.

Top candidate genes	SETI (trimmed mean of bootstrap)	Bias of bootstrap	95% CI of SETI	𝑃	FDR
A5D9H5	1.23; (1.23)	0.12	[1.02, 1.43]	0	0
A6QQB6	1.23; (1.27)	0.09	[1.00, 1.46]	0	0
A0JN96	1.23; (1.23)	0.09	[1.03, 1.43]	0	0
DUFFY	1.23; (1.23)	0.13	[1.02, 1.43]	0	0
A6QP68	1.23; (1.23)	0.10	[1.03, 1.42]	0	0
gi∣11992112	1.23; (1.23)	0.10	[1.05, 1.40]	0	0