Figure 7: Effect of Nrf2 siRNA on mollugin-induced growth inhibition (a), apoptosis (b), and apoptosis-related proteins expression (c). Cells were treated with 40 μM mollugin for indicated times (a). Cells were pretreated with Nrf2 siRNA (250 nM) for 5 h and treated for 3 days with mollugin 40 μm (a)–(c). *Statistically significant difference as compared to control, . #Statistically significant difference as compared to mollugin, . Data are representative of 3 independent experiments.