Protective Effects of p38 MAPK Inhibitor SB202190 against Hippocampal Apoptosis and Spatial Learning and Memory Deficits in a Rat Model of Vascular Dementia

Figure 1

Effect of the p38 MAPK inhibitor SB202190 on expression of p-p38 MAPK in the hippocampus of a vascular dementia (VaD) rat model. Expression of p-p38 MAPK was determined by Western blot and protein expression normalized to β-actin. The data are expressed as means ± standard deviation (SD) (𝑛=6); **𝑃<0.01 versus sham-operated group, ^##𝑃<0.01 SB202190 group versus model group.