Preparation of Biocompatible Carboxymethyl Chitosan Nanoparticles for Delivery of Antibiotic Drug

Table 3

Regression results of equations in vitro release from CCC NPs.

	Zero-order		First-order		Higuchi		Ritger-Peppas		Double exponential
Code	𝑄𝑡=𝐾𝑡		ln(1−𝑄𝑡)=𝐾𝑡		𝑄𝑡=𝐾𝑡^1/2		𝑄𝑡/𝑄∞=𝐾𝑡^𝑛		1−𝑄𝑡=𝐴𝑒^𝛼𝑡+𝐵𝑒^𝛽𝑡
	𝑅^2	𝐾	𝑅^2	𝐾	𝑅^2	𝐾	𝑅^2	𝑛	𝑅^2
F7	0.850	0.072	0.990	0.221	0.971	0.288	0.888	0.638	0.995
F9	0.873	0.072	0.992	0.204	0.977	0.287	0.934	0.639	0.988
F10	0.598	0.060	0.945	0.283	0.831	0.266	0.801	0.337	0.998
F12	0.637	0.061	0.937	0.234	0.858	0.265	0.811	0.374	0.999

Noted “𝑄_𝑡” and “𝑄_∞” are accumulative release rates of CPFX in CCC NPs at time “𝑡” and “∞”.