Review Article

Glucose Toxic Effects on Granulation Tissue Productive Cells: The Diabetics’ Impaired Healing

Figure 4

Common histological aspects of ischemic granulation tissue. Note the presence of an intense inflammatory infiltrate of round cells spread all over the tissue area. The emerging vessels appear unfunctional with thickened walls of fibrohyaline material, “hardened aspect”, and endothelial nuclei hypertrophy. Hematoxylin/eosin staining, ×10 magnification.
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