Identification of Lung-Cancer-Related Genes with the Shortest Path Approach in a Protein-Protein Interaction Network

Table 1

KEGG enrichment analysis of 38 SCLC shortest path genes.

Term	Count^a	Percentage^b	P value	Benjamini adjusted P value
Focal adhesion	8	21.1	1.40𝐸−05	6.70𝐸−04
Regulation of actin cytoskeleton	7	18.4	2.20𝐸−04	5.40𝐸−03
Arrhythmogenic right ventricular cardiomyopathy (ARVC)	5	13.2	2.70𝐸−04	4.40𝐸−03
ECM-receptor interaction	5	13.2	4.00𝐸−04	4.80𝐸−03
Hypertrophic cardiomyopathy (HCM)	5	13.2	4.20𝐸−04	4.10𝐸−03
Dilated cardiomyopathy	5	13.2	5.70𝐸−04	4.60𝐸−03
Cell cycle	5	13.2	1.80𝐸−03	1.20𝐸−02
p53-signaling pathway	4	10.5	2.90𝐸−03	1.70𝐸−02

aThe number of genes belonging to a certain pathway.
bThe percentage of genes belonging to a certain pathway accounts for all the genes undergoing KEGG pathway analysis.