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BioMed Research International
Volume 2013, Article ID 276174, 7 pages
Clinical Study

Content of Trans Fatty Acids in Human Cheek Epithelium: Comparison with Serum and Adipose Tissue

1Department of Cardiac Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India
2Department of Cardiology, All India Institute of Medical Sciences, New Delhi 110029, India
3Department of Surgery, All India Institute of Medical Sciences, New Delhi 110029, India
4Centre for Chronic Disease Control, New Delhi, India

Received 23 April 2013; Revised 29 August 2013; Accepted 30 August 2013

Academic Editor: Kusum Kharbanda

Copyright © 2013 Ransi A. Abraham et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices. Measuring TFA is an arduous task because of the need for fat biopsies. This study identifies a tissue, which can be easily accessed for analytical measurement of trans fatty acid. In this cross-sectional study, fatty acid in adipose tissue, cheek epithelium, and blood samples were assessed by gas chromatography. Spearman correlation coefficient was computed to study the correlation of fatty acid distribution among the three tissues. The correlation coefficient of total trans fatty acid between cheek epithelium and serum was 0.30 ( ) and between cheek epithelium and adipose tissue was 0.33 ( ). This study is the first to report trans fatty acid profile in cheek epithelium giving scope for utilizing the cheek epithelium as a tissue for objective assessment of trans fatty acid intake.