Table 1: Composition and characterization of FLB core tablets

IngredientsQuantity (mg)Core tablet evaluation parameters Observed values

Flurbiprofen100Weight variation (mg)20
Spray dried lactose50.5Core thickness (mm)20
Crospovidone17.5Core diameter (mm)20
Sodium lauryl sulphate1.75Hardness (kg/cm2)6
Talc3.5Friability (%)100.58
Magnesium stearate1.75Disintegration time (sec)3
Core weight 175Content uniformity (%)3
% drug release in 15 min ( ) 3