Colon Targeted Guar Gum Compression Coated Tablets of Flurbiprofen: Formulation, Development, and Pharmacokinetics

Table 5

Release kinetics of FLB-GG compression coated tablets.

Formulation	𝐾	𝑛	𝑅^2	MDT	𝑇10% (h)	𝑇80% (h)
F1	1.4777	3.3104	0.920	2.35	1.6	4.8
F2	1.6240	2.8135	0.919	8.42	2.4	12.0
F3	1.0881	1.4983	0.951	10.34	3.8	14.6
F4	1.0954	1.1592	0.950	11.59	5.6	17.9
F5	1.3280	1.3370	0.928	13.71	5.8	24.0

𝐾: kinetic rate constant, 𝑛: diffusional exponent, 𝑅²: correlation coefficient, MDT: mean dissolution time, 𝑇10%: time to release 10% drug release, and 𝑇80%: time to release 80% drug release.