Acute and Chronic Oral Toxicity of a Partially Purified Plaunotol Extract from Croton stellatopilosus Ohba

Table 1

Observed acute toxicity symptoms and mortality in mice receiving different single doses of PPE.

Dose (g/kg)	Symptoms/Time (Onset to recovery)				Mortality
	Dyspnea	Dullness	Abdominal cramp	Diarrhea	Death/Total	Latency period
Control	None	None	None	None	0/10	—
2.5	None	None	None	6–72 h	0/10	—
5	None	None	None	6–72 h	0/10	—
10	15 min–24 h	15 min–24 h	15 min–24 h	6–96 h	4/10	24 h
20	15 min–24 h	15 min–24 h	15 min–24 h	6–72 h	10/10	24–72 h