Pharmacophore Modeling and Docking Studies on Some Nonpeptide-Based Caspase-3 Inhibitors
Figure 8
Superposition of pharmacophore hypothesis on docked ligand [compound 58 (X1)] at the binding site where the docked ligand is in red color. Hydrogen bonds are expressed in yellow color, and amino acids are expressed in their standard form (H = histidine, C = cysteine, S = serine, R = arginine, W = tryptophan, Y = tyrosine, D = aspartic acid, F = phenylalanine, and E = glutamic acid).
