Research Article

Therapeutic Effect of Exendin-4, a Long-Acting Analogue of Glucagon-Like Peptide-1 Receptor Agonist, on Nerve Regeneration after the Crush Nerve Injury

Figure 1

Sciatic functional index. SFI was calculated by the following formula [13]: . E, and N represent experimental and normal sides, respectively. In the -4 group, the SFI recovered rapidly and returned to the precrush levels by 19 days although in the crush group it did not return to the presurgical level at the end of the study. At 16, 19, 25, and 28 days after the crush injury, the SFIs in the -4 group were significantly higher than those in the crush group ( , compared with crush group).
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