Research Article
Genotyping of CYP2C9 and VKORC1 in the Arabic Population of Al-Ahsa, Saudi Arabia
Table 1
Frequencies of the
CYP2C9*2 and *3 and
VKORC1 –1639G>A genotypes and alleles in a sample of the Saudi Arabian population (
).
| Genotypes and alleles |
No. of individuals, relative frequency, and 95% confidence intervals | (%) | 95% CI |
| CYP2C9 genotype | | | CYP2C9*1/*1 | 90 (68.7) | 60.4–76.2 | CYP2C9*1/*2 | 35 (26.7) | 19.7–34.7 | CYP2C9*1/*3 | 6 (4.6) | 1.9–9.2 | CYP2C9*2/*2 | 0 | — | CYP2C9*2/*3 | 0 | — | CYP2C9*3/*3 | 0 | — | CYP2C9 allele | | | CYP2C9*2 | 35 (13.3) | 9.7–17.9 | CYP2C9*3 | 6 (2.3) | 1.0–4.7 | VKORC1 genotype | | | GG | 49 (37.4) | 29.5–45.9 | GA | 52 (39.7) | 31.6–48.2 | AA | 30 (22.9) | 16.4–30.6 | VKORC1 allele | | | G | 150 (57.3) | 51.2–63.1 | A | 112 (42.7) | 36.9–48.8 |
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