Research Article

Genotyping of CYP2C9 and VKORC1 in the Arabic Population of Al-Ahsa, Saudi Arabia

Table 1

Frequencies of the CYP2C9*2 and *3 and VKORC1 –1639G>A genotypes and alleles in a sample of the Saudi Arabian population ( ).

Genotypes and alleles No. of individuals, relative frequency, and 95% confidence intervals
(%)95% CI

CYP2C9 genotype
CYP2C9*1/*190 (68.7)60.4–76.2
CYP2C9*1/*235 (26.7)19.7–34.7
CYP2C9*1/*36 (4.6)1.9–9.2
CYP2C9*2/*20
CYP2C9*2/*30
CYP2C9*3/*30
CYP2C9 allele
CYP2C9*235 (13.3)9.7–17.9
CYP2C9*36 (2.3)1.0–4.7
VKORC1 genotype
 GG49 (37.4)29.5–45.9
 GA52 (39.7)31.6–48.2
 AA30 (22.9)16.4–30.6
VKORC1 allele
 G150 (57.3)51.2–63.1
 A112 (42.7)36.9–48.8