Gsk-3β Inhibitors Mimic the Cardioprotection Mediated by Ischemic Pre- and Postconditioning in Hypertensive Rats
Figure 9
Representative electron micrographs of mitochondria obtained from nonischemic control (NIC), ischemic control (IC), preconditioned (PRE), postconditioned (POS), LiCl treated (LiClpre and LiClpos), and IMI treated (IMIpre and IMIpos) hearts. Electron microscopy confirmed the presence of mitochondria with dense cristae and intact outer membranes in NIC group while that after ischemia and reperfusion (IC) the organelle appeared swollen with damaged cristae and disrupted membranes. In intervened hearts and especially LiCl treated some mitochondria with normal morphology may be observed.
