Effects of DL-Homocysteine Thiolactone on Cardiac Contractility, Coronary Flow, and Oxidative Stress Markers in the Isolated Rat Heart: The Role of Different Gasotransmitters
Table 1
The effects of DL-Hcy TLHC (a), DL-Hcy TLHC + L-NAME (b), DL-Hcy TLHC + DL-PAG (c), or DL-Hcy TLHC + PPR IX (d) on heart variables in the isolated rat heart (, each substance 10 M, except L-NAME (30 M)).
(a)
max (mmHg/s)
min (mmHg/s)
SLVP (mmHg)
DLVP (mmHg)
MBP (mmHg)
HR (bpm)
Flow (mL/min)
Control ()
DL-Hcy TLHC ()
The values are expressed as the mean ± SE. *Statistical significance (), **high statistical significance ().
(b)
max (mmHg/s)
min (mmHg/s)
SLVP (mmHg)
DLVP (mmHg)
MBP (mmHg)
HR (bpm)
Flow (mL/min)
Control ()
DL-Hcy TLHC + L-NAME ()
The values are expressed as the mean ± SE. **High statistical significance ().
(c)
max (mmHg/s)
min (mmHg/s)
SLVP (mmHg)
DLVP (mmHg)
MBP (mmHg)
HR (bpm)
Flow (mL/min)
Control ()
DL-Hcy TLHC + DL-PAG ()
The values are expressed as the mean ± SE. *Statistical significance (), **high statistical significance ().
(d)
max (mmHg/s)
min (mmHg/s)
SLVP (mmHg)
DLVP (mmHg)
MBP (mmHg)
HR (bpm)
Flow (mL/min)
Control ()
DL-Hcy TLHC + PPR IX ()
The values are expressed as the mean ± SE. *Statistical significance ().
