BioMed Research International / 2013 / Article / Fig 1

Research Article

DHA Inhibits Protein Degradation More Efficiently than EPA by Regulating the PPARγ/NFκB Pathway in C2C12 Myotubes

Figure 1

Effect of n-3 PUFA on total protein degradation in C2C12 myotubes. C2C12 myotubes were incubated (24 hours) with increasing concentrations of EPA (▲) or DHA (■), respectively. The radioactivity associated with cellular proteins is shown in the presence of 300 μM, 400 μM, 500 μM or 600 μM EPA, or DHA, respectively. Each treatment mean ( ) reported as a percentage of a FFA-free control; bars, SE. a, differences from controls in the presence of EPA ( ) and b, differences from the presence of DHA ( ). EPA = eicosapentaenoic acid, DHA = docosahexaenoic acid.

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