Detection of the Epstein-Barr Virus and DNA-Topoisomerase II-α in Recurrent and Nonrecurrent Giant Cell Lesion of the Jawbones

Table 1

Immunohistochemical findings of EBV and Topo II-α in giant cell lesion of jawbones.

Lesions	No. of cases	EBV				Topo II-α LI (%)^a	Topo II-α LI (%)^b
		−	+	++	+++
PGCL	9	9	0	0	0	5.70 ± 2.02	16.81 ± 2.64
CGCL	13	12	1	0	0	7.64 ± 0.63	22.90 ± 5.62
GCT	2	0	0	2	0	11.42 ± 4.02	39.22 ± 5.75

MGCs: multinucleated giant cells; MSCs: mononuclear stromal cells.
^aMean ± standard deviation of Topo II-αin MGCs.
^bMean ± standard deviation of Topo II-α in MSCs.