Implementation of High Resolution Whole Genome Array CGH in the Prenatal Clinical Setting: Advantages, Challenges, and Review of the Literature
FISH analysis showing the confirmation of the unbalanced translocation in Case , using subtelomeric probes for chromosomes 9 and 17. Chromosome 8p and q probes (b) are also included in the probe mixture used (VYSIS, ToTelVysion probes). (a) Probes used: subtelomeric 9p and 17q, the top red arrow points at the derivative chromosome 9 (showing the deletion of 9q) and the green arrows point at chromosome 17. (b) Probes used: subtelomeric 17p, 8p and 8q, the red arrow points at the derivative chromosome 9 (showing the duplication of 17p) the green arrows point at chromosome17p.