Poly-S-Nitrosated Albumin as a Safe and Effective Multifunctional Antitumor Agent: Characterization, Biochemistry and Possible Future Therapeutic Applications
Figure 3
Effect of Poly-SNO-HSA on tumor growth in LY-80 tumor-bearing rats. LY-80 tumor-bearing rats were given daily intratumor injections of saline (5 mL/kg; open squares), HSA (10 μmol/5 mL/kg; open circles), or Poly-SNO-HSA (10 μmol/5 mL/kg; closed circles) for 7 days (day 5–11 after inoculation with tumor cells). Results are means ± SD; animals per experimental group. *Statistically significant reduction in tumor growth as compared with treatment with saline () or HSA () at the corresponding time. **Statistically significant reduction as compared with treatment with saline () or HSA () at the corresponding time [29, 30].
