Research Article

Comparative Gene Expression Profiling in Human Cumulus Cells according to Ovarian Gonadotropin Treatments

Table 2

List of genes that were significantly upregulated in rFSH CCs compared with HP-hMG CCs.

Gene nameGene titleProbesetsFold changeFDR (%)

ITM2AIntegral membrane protein 2A202746_at4.20
H19H19, imprinted maternally expressed transcript (nonprotein coding)224646_x_at3.80
PSPHPhosphoserine phosphatase205048_s_at2.40
GALGalanin214240_at2.40
ZNF528Zinc finger-like232315_at2.30
NFKBIZNuclear factor of kappa light polypeptide gene enhancer in B-cell inhibitor, zeta223217_s_at2.24.73
FAM84BBreast cancer membrane protein 101225864_at20
COL3A1Collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)211161_s_at21.53
DKFZp451A211DKFZp451A211 protein1556114_a_at1.80
SPARCL1SPARC-like 1 (mast9, hevin)200795_at1.80
PTERPhosphotriesterase related222798_at1.80
NFIBNuclear factor I/B213032_at1.80
MXRA5Adlican209596_at1.80
GALNTL2UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2228501_at1.80
SUPT3HSuppressor of Ty 3 homolog (S. cerevisiae)211106_at1.70
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 /// DEAD (Asp-Glu-Ala-Asp) box polypeptide 17208151_x_at1.74.15
TNFAIP6Tumor necrosis factor, alpha-induced protein 6206026_s_at1.71.05
MTUS1Mitochondrial tumor suppressor 1212096_s_at1.74.73
RP1-93H18.5Similar to RIKEN cDNA A630077B13 gene, RIKEN cDNA 2810048G17229390_at1.70
LOC92196Hypothetical LOC92196 (uncharacterized)229290_at1.60
LOC401317Hypothetical LOC402472 (uncharacterized)242329_at1.60
CHAC1Hypothetical protein MGC4504219270_at1.60
STRN3Striatin, calmodulin binding protein 3215505_s_at1.60
OSBPL10Oxysterol binding protein-like 10219073_s_at1.60
GLIPR1HIV-1 rev binding protein 2214085_x_at1.60
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase237862_at1.60
TNFAIP8Tumor necrosis factor, alpha-induced protein 8208296_x_at1.60.54
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1204286_s_at1.60
RBM24RNA binding motif protein 24235004_at1.61.53
LOC388796Hypothetical LOC388796 (uncharacterized)65588_at1.60
LOC157278Homo sapiens, clone IMAGE:5285282, mRNA (uncharacterized)238716_at1.60
GREM1Gremlin 1218468_s_at1.60
OSBPL6Oxysterol binding protein-like 6223805_at1.60
CREB5cAMP responsive element binding protein 5205931_s_at1.50
CAMK1DCalcium/calmodulin-dependent protein kinase ID235626_at1.50
CCDC58Hypothetical LOC131076235244_at1.50
LRRN3Leucine-rich repeat neuronal 3209840_s_at1.50
HS3ST3A1Heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1219985_at1.50
ARSDArylsulfatase D232423_at1.50
ENDOD1KIAA0830 protein212570_at1.50
ZNF521Zinc finger protein 521226676_at1.50
DFNA5Deafness, autosomal dominant 5203695_s_at1.50
PSD3Pleckstrin and Sec7 domain containing 3203354_s_at1.50
LOC283070Hypothetical protein LOC283070 (uncharacterized)226382_at1.50
COL1A1Collagen, type I, alpha 11556499_s_at1.50
SPOCK2Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2202523_s_at1.50
ATP7AATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)205197_s_at1.50
MT3Metallothionein 3 (growth inhibitory factor (neurotrophic))205970_at1.50
DDIT3DNA-damage-inducible transcript 3209383_at1.50