SNP rs2073618 of the Osteoprotegerin Gene Is Associated with Diabetic Retinopathy in Slovenian Patients with Type 2 Diabetes

Table 3

Association between OPG polymorphisms and the risk for DR.

Polymorphism	Model	Number of cases/controls	OR* (95% CI)	P value
rs2073618; (c.9C>G)	Codominant:
	CC versus GG (reference)	70/66 versus 78/135	2.19 (1.18–4.09)	0.01
	CG versus GG (reference)	132/164 versus 78/135	1.51 (0.93–2.47)	0.098
	Dominant:
	CC + CG versus GG (reference)	202/230 versus 78/135	1.72 (1.08–2.70)	0.022
	Recessive:
	CC versus CG + GG (reference)	70/66 versus 210/299	1.75 (1.0–3.05)	0.05
rs3134069; (g.119964988A>C)	Dominant:
	CC + AC versus AA (reference)	54/37 versus 226/328	1.25 (0.67–2.33)	0.491
	Recessive:
	CC versus AC + AA (reference)	6/1 versus 274/364	4.8 (0.45–50.8)	0.19

∗Adjusted for duration of diabetes, insulin therapy, BMI, HbA_1c, total LDL, HDL, and cholesterol levels.
Bold indicates statistically significant results.