Omega-3 Fatty Acids Inhibit Tumor Growth in a Rat Model of Bladder Cancer

Table 1

Omega-3 effects on bladder cancer chemoprevention: macroscopic (quantitative) and microscopic (qualitative) evaluation of urothelial lesions.

Macroscopy (quantitative) & microscopy (qualitative)	Control; (𝑛=8)	Omega-3; (𝑛=8)	BBN; (𝑛=20)	Omega-3 + BBN; (𝑛=8)
Tumor number
Rats with tumor [% (𝑛/𝑛)]	0	0	65.0 (13 in 20)	62.5 (5 in 8)
Tumors/rat [mean (𝑛/𝑛)]	0	0	1.2±0.1 (16 in 13)	1.2±0.2 (6 in 5)
Tumor volume
Mean/rat [mm^3 (𝑛)]	0	0	138.5±7.5 (in 13)	1.1±0.1 (in 5)
Mean/tumor [mm^3 (𝑛)]	0	0	112.5±6.4 (in 16)	0.9±0.1 (in 6)
Preneoplasic lesions [% (𝑛/𝑛)]
Hyperplasia	0	0	100 (20 in 20)	87.5 (7 in 8)
High-grade dysplasia	0	0	100 (20 in 20)	0 (0 in 8)
Neoplasic lesions [% (𝑛/𝑛)]
Papillary tumor	0	0	100 (13 in 13)	100 (5 in 5)
Infiltrative tumor	0	0	15 (2 in 13)	0 (0 in 5)
Carcinoma in situ	0	0	31 (4 in 13)	0 (0 in 5)