Omega-3 Fatty Acids Inhibit Tumor Growth in a Rat Model of Bladder Cancer

Table 2

Safety profile: biochemical and hematological data.

Parameters	Control; (𝑛=8)	Omega-3; (𝑛=8)	BBN; (𝑛=20)	Omega-3 + BBN; (𝑛=8)
Biochemical data
Glucose (mmol/L)	9.90±0.54	9.52±0.48	10.22±0.61	9.84±0.52
Creatinine (mmol/L)	51.53±1.68	35.36±1.84^aaa	54.81±1.72	32.90±1.64^aaabbb
Total-c (mmol/L)	1.39±0.06	1.21±0.07	1.31±0.05	1.43±0.06
TGs (mmol/L)	1.73±0.1	0.93±0.03^aa	1.47±0.1	0.96±0.11^aabb
AST (IU/L)	51.57±1.09	62.00±1.08	77.18±4.9^aaa	73.86±3.45^aaa
ALT (IU/L)	30.86±1.75	23.00±0.91	36.17±2.32	38.63±1.86
Hematological data
RBC count (10^12/L)	7.58±0.29	7.79±0.58	8.07±0.11	7.47±0.15
HCT (pp of 1.0)	0.40±0.02	0.40±0.03	0.42±0.004	0.38±0.009
HGB (g/L)	141.5±5.24	139.5±8.63	146±1.47	137.3±3.09
PLT (×10^9/L)	990.67±46.21	760.8±77.07	1008.13±46.96	811.00±37.13^b
PCT (pp of 1.0)	0.0057±0.0002	0.004±0.0004^aa	0.005±0.0002	0.0047±0.0002^ab

Values are mean ± SEM. ^aa𝑃<0.01 and ^aaa𝑃<0.001 versus control; ^b𝑃<0.05, ^bb𝑃<0.01 and ^bbb𝑃<0.001 versus BBN.