No Immunogenicity of IPS Cells in Syngeneic Host Studied by In Vivo Injection and 3D Scaffold Experiments
Figure 5
Lack of immunogenicity of myeloid differentiated MEF iPSCs in syngenic recipient. Myeloid differentiated MEF iPSCs (1 × 105) cultured in scaffolds for 2 weeks. They were transplanted into C57BL/6 or BALB/c mice. (a) Hematoxylin and eosin staining of the scaffolds operated at day 6 and 20. (b) The number of cells in the scaffold was counted at a magnification of 400x. (). Tissue sections of the explanted scaffold are with FITC-labeled anti-CD4 and PE-labeled anti-CD8. The graph shows the average number of CD8 (c) or CD4 (d) positive cells at day 0, day 6 and day 20, respectively (). Error bars represent standard deviation.
