BioMed Research International / 2013 / Article / Fig 2

Research Article

High Expression of H3K27me3 Is an Independent Predictor of Worse Outcome in Patients with Urothelial Carcinoma of Bladder Treated with Radical Cystectomy

Figure 2

The expression of H3K27me3 in UCB and adjacent normal bladder tissues by IHC. (a) High expression of H3K27me3 was shown in a UCB case (case 25), in which more than 80% of carcinoma cells revealed positive staining of H3K27me3 protein in nuclei (100X). (b) Another UCB case (case 34) demonstrated low expression of H3K27me3, in which less than 30% of carcinoma cells showed positive staining of H3K27me3 protein in nuclei (100X). (c) Adjacent normal bladder urothelial mucosal tissue showed nearly negative expression of H3K27me3 protein (100X). The lower panels indicated the higher magnification (400X) from the area of the box in the upper panels.

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