BioMed Research International / 2013 / Article / Tab 2

Research Article

High Expression of H3K27me3 Is an Independent Predictor of Worse Outcome in Patients with Urothelial Carcinoma of Bladder Treated with Radical Cystectomy

Table 2

Univariate analysis of H3K27m3 expression and various clinicopathological parameters in 126 patients with UCB.

CharacteristicTotal casesRR (95% CI) value

Age, years0.786
 ≤65*681
 >65581.090 (0.586–2.027)
Gender0.675
 Male1141
 Female120.777 (0.239–2.523)
Tumor multiplicity0.026
 Unifocal491
 Multifocal772.025 (1.088–3.771)
WHO grade0.330
 G1241
 G2462.069 (0.757–5.655)
 G3562.016 (0.751–5.412)
pT status<0.001
 PT1251
 PT2551.047 (0.363–3.017)
 PT3302.561 (0.908–7.219)
 PT4166.577 (2.250–19.227)
pN status<0.001
 PN−1051
 PN+214.957 (2.573–9.549)
H3K27me3<0.001
 Low expression671
 High expression596.476 (2.857–14.676) 

Median age; RR: relative risk; CI: confidence interval; UCB: urothelial carcinoma of bladder.

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