/ / / Tab 2

Research Article

High Expression of H3K27me3 Is an Independent Predictor of Worse Outcome in Patients with Urothelial Carcinoma of Bladder Treated with Radical Cystectomy

Table 2

Univariate analysis of H3K27m3 expression and various clinicopathological parameters in 126 patients with UCB.


Characteristic	Total cases	RR (95% CI)	value

Age, years			0.786
≤65*	68	1
>65	58	1.090 (0.586–2.027)
Gender			0.675
Male	114	1
Female	12	0.777 (0.239–2.523)
Tumor multiplicity			0.026
Unifocal	49	1
Multifocal	77	2.025 (1.088–3.771)
WHO grade			0.330
G1	24	1
G2	46	2.069 (0.757–5.655)
G3	56	2.016 (0.751–5.412)
pT status			<0.001
PT1	25	1
PT2	55	1.047 (0.363–3.017)
PT3	30	2.561 (0.908–7.219)
PT4	16	6.577 (2.250–19.227)
pN status			<0.001
PN−	105	1
PN+	21	4.957 (2.573–9.549)
H3K27me3			<0.001
Low expression	67	1
High expression	59	6.476 (2.857–14.676)

Median age; RR: relative risk; CI: confidence interval; UCB: urothelial carcinoma of bladder.

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