Concerted Action of ANP and Dopamine D1-Receptor to Regulate Sodium Homeostasis in Nephrotic Syndrome

Figure 3

Urinary excretion of sodium (a) and cGMP (b) in control and PAN-NS rats before (𝑡=0--120 min, Basal), during (𝑡=120--150 min, VE), and after (𝑡=150--180 min, R-VE) volume expansion (VE), seven days after injection. Bars represent means of 3 to 4 experiments per group and error bars represent SE. *𝑃<0.05, significantly different from control rats within the same treatment group; ⁺𝑃<0.05, significantly different from vehicle treatment. ^#𝑃<0.05, significantly different from zaprinast treatment.

(a)

(b)