In Vitro Cytotoxicity and In Vivo Acute and Chronic Toxicity of Xanthii Fructus and Its Processed Product

Table 7

Kidney and liver pathological damage occurrence rates (%) in chronic toxicity assays.

Groups	I	II	III	IV	V	VI	VII
Kidney
Tubular edema	0	25	50	0	33	0	50
Renal interstitial; Inflammatory infiltration	0	50	75	0	33	0	25
Renal tubular exudation	0	50	75	50	33	0	25
Tubular necrosis	0	25	50	0	33	0	25
Fibrosis	0	0	0	0	0	0	0
Liver
Liver cell edema	0	25	0	25	50	75	25
Spotty necrosis	0	75	100	0	50	0	25
Focal necrosis	0	25	50	0	25	0	0
Inflammation	0	0	50	0	25	0	0
Fibrosis	0	0	0	0	0	0	0