Reduced T Cell Receptor Excision Circle Levels in the Colonic Mucosa of Microscopic Colitis Patients Indicate Local Proliferation rather than Homing of Peripheral Lymphocytes to the Inflamed Mucosa
Figure 1
Human colonic biopsies showing (a) normal colonic mucosa; (b) typical findings of lymphocytic colitis, including epithelial cell damage with increased numbers of IELs, and infiltration of lymphocytes in the lamina propria; (c) typical findings of collagenous colitis, including increased thickness of the subepithelial collagen layer, inflammation of lamina propria, and epithelial cell damage with IELs. Photo: Sune Eriksson Department of Pathology, Örebro University Hospital. ((a) and (b)) H&E Staining, (c) Van Gieson Staining.