Review Article

The Effects of Bariatric Procedures versus Medical Therapy for Obese Patients with Type 2 Diabetes: Meta-Analysis of Randomized Controlled Trials

Table 5

Adverse events of studies in meta-analysis ( ).

Study Bariatric surgeryMedication

Dixon et al., 2008 [13]Gastric bandingSuperficial wound infection (1), gastric pouch enlargement (2), regurgitation (1), febrile episodes (1), hypoglycemic (1), and gastrointestinal intolerance to metformin (1).Gastrointestinal tract adverse effects (2), persistent diarrhea with metformin (1), vasculitic rash (1), multiple hypoglycemic (1), angina and a transient cerebral ischemic (1), and intolerant of very low-calorie meal (2).

Schauer et al., 2012 [14]Gastric bypassHospitalization (11), dehydration (4), reoperation (3), transfusion (1), hemoglobin decrease 5 g/dL (1), transient renal insufficiency (1), cholelithiasis (1), ketoacidosis (1), wound infection (1), pneumonia (2), hernia (1), hypoglycemic episodes (35), anemia (6), anastomotic ulcer (4), and hypokalemia (2).Requiring hospitalization (4), arrhythmia or palpitations (2), cellulitis (1), kidney stone (1), hypoglycemic episodes (39), anemia (3), hypokalemia (1), and excessive weight gain (3).
GastrectomyHospitalization (4), dehydration (2), reoperation (1), transfusion (1), gastrointestinal leak (1), arrhythmia or palpitations (1), pleural effusion (1), hypoglycemic episodes (28), anemia (6), and hypokalemia (2).

Mingrone et al., 2012 [15]Gastric bypassIntestinal occlusion (1) and iron-deficiency anemia (2).Persistent diarrhea associated with Metformin (2).
Biliopancreatic
diversion
Incisional hernia (1), iron-deficiency anemia (2), hypoalbuminemia (2), osteopenia (1), and osteoporosis (1).

Total128/148 (86.49%)64/89 (71.91%)